Educational Qualifications
Degree
Institution
Year
Ph.D Kurukshetra University Kurukshetra
2001
and IG I B (CSIR) , Delhi
M.Sc. (Biochem) Kurukshetra University.
Kurukshetra
1995
Professional Experience
|
Year |
Title |
Specialty/Discipline |
Place
|
| 01/06 |
Research Officer |
Biochemistry noate |
Regional Research Institute (Ay.),Nehru Garden, Kothrud, Pune-38 |
| 8/03-/1/06 |
Lecture |
Biochemistry Biomedical Sciences, |
Bundelkhand University, Jhansi-28. |
| 1/03-8/03 |
Post Doc |
Structural Biology HIM |
Harvard, Boston, MA, US. 02115. |
| 8/01-1/03 |
Post Doc |
Structure Biology |
City of Hope, Duarte, CA, 91010. USA. |
Patents Granted
1.
Sharma,Gainda Lal; Dabur,Rajesh;Ali,Mohammad. 2002. Antifungal molecule 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
methylethyl pentanoate
United States Patent 6713504. http://www.freepatentsonline.com/6713504.html .
2.
Rajesh, GL Sharma and M Ali (2001) . A novel antifungal molecule characterized from D. metel . European patent, Granted: 02718466.2-
2101 IB0201207.
3.
Rajesh, GL Sharma and M Ali (2001). A process for isolation of novel antifungal lead molecule. (Indian Patent NF 343/NF/2001).
4.
Rajesh, GL Sharma and M Ali (2001). A novel antifungal molecule 2-(3, 4-dimethyl-2, 5-dihydro-1h-pyrrol-2-yl)-1-methylethyl
pentanoate. Indian Patent 28-09-01 .
Papers Published
1. V. Yadav, R Mandhan, Q Pasha, S. Pasha, A Katyal, AK Chhillar, J Gupta,
R Dabur and GL Sharma (2007). Isolation and characterization
of an antifungal protein from Escherichia coli .
J. Med Microbiol. 56: 637-644.
2.
Dabur R, Mandal TK, Sharma GL (2007). Post antifungal effects of antifungal compound 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
methylethyl pentanoate.
J Med Microbiol . 56: 815-818.
3. Gupta, J; Chattopadhaya, D; Bhadoria, D P; Pasha, MAQ; Gupta, Vijay; Kumar, M;
Dabur, R; Yadav, V; Sharma, GL (2007). T-lymphocyte
subset profile and serum alpha-1-antitrypsin in pathogenesis of chronic obstructive pulmonary disease.
Clinical and Experimental
Immunology . 149 ( 3 ): 463-9 . Epub 2007 Jun 12. PMID: 17565607 [PubMed - indexed for MEDLINE] .
4. Sawaya MR, Zhu Z, Mersha F, Chan SH, Dabur R, Xu SY, Balendiran GK. Crystal structure of the restriction-modification system control
element C.Bclland mapping of its binding site.
Structure . 2005 Dec; 13(12):1837-47. PMID: 16338412 [PubMed - indexed for MEDLINE]
5.
Dabur R, Mandal TK, Sharma GL (2007). Post antifungal effects of antifungal compound 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
methylethyl pentanoate.
J Med Microbiol . 56: 815-818.
6. Gupta, J; Chattopadhaya, D; Bhadoria, D P; Pasha, MAQ; Gupta, Vijay; Kumar, M;
Dabur, R; Yadav, V; Sharma, GL (2007). T-lymphocyte
subset profile and serum alpha-1-antitrypsin in pathogenesis of chronic obstructive pulmonary disease.
Clinical and Experimental
Immunology . ( In Press ).
7. Tiwari RK, Singh D, Singh J, Yadav V, Pathak AK,
Dabur R, Chhillar AK, Singh R, Sharma GL, Chandra R, Verma AK. Synthesis and
antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino[1,2-a] indoles.
Bioorg Med Chem Lett . 2006 Jan 15; 16(2):413-6. Epub
2005 Oct 21. PMID: 16246547 [PubMed - indexed for MEDLINE]
8. Chhillar AK, Arya P, Mukherjee C, Kumar P, Yadav Y, Sharma AK, Yadav V,Gupta J,
Dabur R, Jha HN, Watterson AC, Parmar VS, Prasad
AK, Sharma GL. Microwave-assisted synthesis of antimicrobial dihydropyridines and tetrahydropyrimidin-2-ones: novel compounds
against aspergillosis.
Bioorg Med Chem. 2006 Feb 15; 14(4):973-81. Epub 2005 Oct 7. PMID: 16214352 [PubMed - indexed for MEDLINE]
9.
Dabur R, Diwedi SK, Yadav V, Mishra V, Singh R, Singh H, Sharma GL. Efficacy of 2-(3,4-dimethyl-2,5-dihydro-1h-pyrrole-2-yl)-1-
methylethylpentanoate in a murine model of invasive aspergillosis.
Antimicrob Agents Chemother. 2005 Oct; 49(10):4365-7. PMID:
16189123 [PubMed - indexed for MEDLINE]
10. Yadav V, Gupta J, Mandhan R, Chhillar AK,
Dabur R, Singh DD, Sharma GL. Investigations on anti-Aspergillus properties of bacterial
products.
Lett Appl Microbiol
. 2005; 41(4):309-14. PMID: 16162136 [PubMed - indexed for MEDLINE]
11. Dabur R, Chhillar AK, Yadav V, Kamal PK, Gupta J, Sharma GL. In vitro antifungal activity of 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
methylethyl pentanoate, a dihydropyrrole derivative.
J Med Microbiol . 2005 Jun; 54(Pt 6):549-52. PMID: 15888463 [PubMed - indexed
for MEDLINE]
12. Gupta J, Bhadoria DP, Lal MK, Kukreti R, Chattopadhaya D, Gupta VK,
Dabur R, Yadav V, Chhillar AK, Sharma GL. Association of the
PIM3 allele of the alpha-1-antitrypsin gene with chronic obstructive pulmonary disease.
Clin Biochem. 2005 May; 38(5):489-91. PMID:
15820782 [PubMed - indexed for MEDLINE]
13. Yadav V, Mandhan R,
Dabur R, Chhillar AK, Gupta J, Sharma GL. A fraction from Escherichia coli with anti-Aspergillus properties.
J Med
Microbiol . 2005 Apr; 54(Pt 4):375-9. PMID: 15770023 [PubMed - indexed for MEDLINE]
14. Clark J, Shevchuk T, Swiderski PM,
Dabur R, Crocitto LE, Buryanov YI, Smith SS. Construction of ordered protein arrays.
Methods Mol
Biol. 2005; 300:325-48. Review. PMID: 15657490 [PubMed - indexed for MEDLINE]
15. Ashok K. Prasad, Vineet Kumar, Pragya Arya, Sarvesh Kumar,
Rajesh Dabur , Naresh Singh, Anil K. Chhillar, Gainda L. Sharma, Balaram
Ghosh, Jesper Wengel, Carl E. Olsen, and Virinder S. Parmar. Investigations toward new lead compounds from medicinally important
plants.
Pure Appl. Chem. 77(1), 25-40, 2005. DOI: 10.1351/pac200577010025.
16. Balendiran GK,
Dabur R, Fraser D. The role of glutathione in cancer.
Cell Biochem Funct . 2004 Nov-Dec; 22(6):343-52. Review. PMID:
15386533 [PubMed - indexed for MEDLINE]
17.
Dabur R, Ali M, Singh H, Gupta J, Sharma GL. A novel antifungal pyrrole derivative from Datura metel leaves.
Pharmazie. 2004 Jul; 59(7)
:568-70. PMID: 15296098 [PubMed - indexed for MEDLINE]
18.
Dabur R, Singh H, Chhillar AK, Ali M, Sharma GL. Antifungal potential of Indian medicinal plants.
Fitoterapia. 2003 Jun; 75(3-4):389-91.
PMID: 15159003 [PubMed - indexed for MEDLINE]
19. A.K. Ashok, V. Kumar, P. Arya, S. Kumar,
R. Dabur, N. Singh, A.K. Chhillar, G.L. Sharma, B. Ghosh, J. Wengel , C.E. Olsen and V.S.
Parmar: Investigations towards new lead compounds from medicinally important plants.
In Proceedings of bioresources towards
drug discovery and development (2004), p. 213-235, ISBN No: 99903-73-16-7.
20. Clark J, Shevchuk T, Swiderski PM,
Dabur R, Crocitto LE, Buryanov YI, Smith SS. Mobility-shift analysis with microfluidics chips.
Biotechniques. 2003 Sep; 35(3):548-54. PMID: 14513560 [PubMed - indexed for MEDLINE]
21.
Rajesh and Sharma G L (2002). Studies on antimycotic properties of Datura metel .
J Ethanopharmacol (80) 193-197. [PubMed -
indexed for MEDLINE]
22.
Dabur R, Mandal TK, Gurav AM, Singh DD. Bajpai V, GS Lavekar. (2007). Antibacterial and Antifungal Potential of some Indian medicinal
plants
Afr J Trad CAM. 4(3):319-322.
23.
Dabur R, Mandal TK, Gurav AM, Tasleem Arif, Singh DD. Bajpai V, Chandra K. (2007). Antibacterial and Antifungal Potential of two
Blumea species used in folkloric medicine. Bull Medico-Ethno- Bot. Res . (In Correspondence).
Books
1.Jarrod Clark; Taras Schevchuk; Piotr M Swiderski; Rajesh Dabur; Laura E Crocitto; Yaroslav I Buryanov and Steven S Smith (2003).
Construction of Ordered protein Arrays . Academic Press, Inc. A Division of Harcourt Brace & Company, 525 B Street, Suite1900, San
Diego, California, 92101-4495.
2.K. Chandra, BG Choudhary,
Rajesh Dabur, TK Mandal, AM Gurav, MB Yelne (2007).
Database of Important Medicinal Plants
Volume-VIII. CCRAS Press, Govt of India, New Delhi. In Press.
Visits
December, 2001 State University of New York (SUNY) at Stony Brook, New York.
March, 2001 Beckman
Research Centre, Duarte , California, USA.
June-August 2002 Stanford University, Stanford, California, USA.
January 2003 Harvard Institute of Medicine, Boston, MA, USA.