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Dr Rajesh Dabur


Research Officer (Ay)
Phone: 020-25383138/ 25380326 Fax: 020-25386715
E-mail:
rajeshdabur@nic.in

Educational Qualifications 
           

Degree                   Institution                                                     Year

Ph.D                         Kurukshetra University Kurukshetra               2001
                                 and IG I B (CSIR) , Delhi
M.Sc. (Biochem)      Kurukshetra University. Kurukshetra              1995                                      

Professional Experience

Year      Title  Specialty/Discipline    Place
01/06 Research Officer Biochemistry noate Regional Research Institute (Ay.),Nehru Garden, Kothrud, Pune-38
8/03-/1/06 Lecture Biochemistry Biomedical Sciences, Bundelkhand University, Jhansi-28.
1/03-8/03 Post Doc Structural Biology HIM Harvard, Boston, MA, US. 02115.
8/01-1/03 Post Doc Structure Biology City of Hope, Duarte, CA, 91010. USA.


Patents Granted

1.Sharma,Gainda Lal; Dabur,Rajesh;Ali,Mohammad. 2002. Antifungal molecule 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
   methylethyl  pentanoate  United States Patent 6713504. http://www.freepatentsonline.com/6713504.html .
2. Rajesh, GL Sharma and M Ali (2001) . A novel antifungal molecule characterized from D. metel . European patent, Granted: 02718466.2-
    2101  IB0201207.
3. Rajesh, GL Sharma and M Ali (2001). A process for isolation of novel antifungal lead molecule. (Indian Patent NF 343/NF/2001).
4. Rajesh, GL Sharma and M Ali (2001). A novel antifungal molecule 2-(3, 4-dimethyl-2, 5-dihydro-1h-pyrrol-2-yl)-1-methylethyl
    pentanoate. Indian Patent 28-09-01 .

Papers Published

1. V. Yadav, R Mandhan, Q Pasha, S. Pasha, A Katyal, AK Chhillar, J Gupta, R Dabur and GL Sharma (2007). Isolation and characterization
    of an antifungal protein from Escherichia coli . J. Med Microbiol. 56: 637-644.

2. Dabur R, Mandal TK, Sharma GL (2007). Post antifungal effects of antifungal compound 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
    methylethyl pentanoate. J Med Microbiol . 56: 815-818.

3. Gupta, J; Chattopadhaya, D; Bhadoria, D P; Pasha, MAQ; Gupta, Vijay; Kumar, M; Dabur, R; Yadav, V; Sharma, GL (2007). T-lymphocyte
    subset profile and serum alpha-1-antitrypsin in pathogenesis of chronic obstructive pulmonary disease. Clinical and Experimental
    Immunology
. 149 ( 3 ): 463-9 . Epub 2007 Jun 12. PMID: 17565607 [PubMed - indexed for MEDLINE] .

4. Sawaya MR, Zhu Z, Mersha F, Chan SH, Dabur R, Xu SY, Balendiran GK. Crystal structure of the restriction-modification system control
    element C.Bclland mapping of its binding site. Structure . 2005 Dec; 13(12):1837-47. PMID: 16338412 [PubMed - indexed for MEDLINE]

5. Dabur R, Mandal TK, Sharma GL (2007). Post antifungal effects of antifungal compound 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
    methylethyl pentanoate. J Med Microbiol . 56: 815-818.

6. Gupta, J; Chattopadhaya, D; Bhadoria, D P; Pasha, MAQ; Gupta, Vijay; Kumar, M; Dabur, R; Yadav, V; Sharma, GL (2007). T-lymphocyte
    subset profile and serum alpha-1-antitrypsin in pathogenesis of chronic obstructive pulmonary disease. Clinical and Experimental
    Immunology . ( In Press )
.

7. Tiwari RK, Singh D, Singh J, Yadav V, Pathak AK, Dabur R, Chhillar AK, Singh R, Sharma GL, Chandra R, Verma AK. Synthesis and
    antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino[1,2-a] indoles. Bioorg Med Chem Lett . 2006 Jan 15; 16(2):413-6. Epub
    2005 Oct 21. PMID: 16246547 [PubMed - indexed for MEDLINE]

8. Chhillar AK, Arya P, Mukherjee C, Kumar P, Yadav Y, Sharma AK, Yadav V,Gupta J, Dabur R, Jha HN, Watterson AC, Parmar VS, Prasad
    AK, Sharma GL. Microwave-assisted synthesis of antimicrobial dihydropyridines and tetrahydropyrimidin-2-ones: novel compounds
    against aspergillosis. Bioorg Med Chem. 2006 Feb 15; 14(4):973-81. Epub 2005 Oct 7. PMID: 16214352 [PubMed - indexed for MEDLINE]

9. Dabur R, Diwedi SK, Yadav V, Mishra V, Singh R, Singh H, Sharma GL. Efficacy of 2-(3,4-dimethyl-2,5-dihydro-1h-pyrrole-2-yl)-1-
   methylethylpentanoate in a murine model of invasive aspergillosis. Antimicrob Agents Chemother. 2005 Oct; 49(10):4365-7. PMID:
    16189123 [PubMed - indexed for MEDLINE]

10. Yadav V, Gupta J, Mandhan R, Chhillar AK, Dabur R, Singh DD, Sharma GL. Investigations on anti-Aspergillus properties of bacterial
      products. Lett Appl Microbiol . 2005; 41(4):309-14. PMID: 16162136 [PubMed - indexed for MEDLINE]

11. Dabur R, Chhillar AK, Yadav V, Kamal PK, Gupta J, Sharma GL. In vitro antifungal activity of 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-
      methylethyl pentanoate, a dihydropyrrole derivative. J Med Microbiol . 2005 Jun; 54(Pt 6):549-52. PMID: 15888463 [PubMed - indexed
      for MEDLINE]

12. Gupta J, Bhadoria DP, Lal MK, Kukreti R, Chattopadhaya D, Gupta VK, Dabur R, Yadav V, Chhillar AK, Sharma GL. Association of the
      PIM3 allele of the alpha-1-antitrypsin gene with chronic obstructive pulmonary disease. Clin Biochem. 2005 May; 38(5):489-91. PMID:
      15820782 [PubMed - indexed for MEDLINE]


13. Yadav V, Mandhan R, Dabur R, Chhillar AK, Gupta J, Sharma GL. A fraction from Escherichia coli with anti-Aspergillus properties. J Med
      Microbiol
. 2005 Apr; 54(Pt 4):375-9. PMID: 15770023 [PubMed - indexed for MEDLINE]

14. Clark J, Shevchuk T, Swiderski PM, Dabur R, Crocitto LE, Buryanov YI, Smith SS. Construction of ordered protein arrays. Methods Mol
      Biol
. 2005; 300:325-48. Review. PMID: 15657490 [PubMed - indexed for MEDLINE]

15. Ashok K. Prasad, Vineet Kumar, Pragya Arya, Sarvesh Kumar, Rajesh Dabur , Naresh Singh, Anil K. Chhillar, Gainda L. Sharma, Balaram
      Ghosh, Jesper Wengel, Carl E. Olsen, and Virinder S. Parmar. Investigations toward new lead compounds from medicinally important
      plants. Pure Appl. Chem. 77(1), 25-40, 2005. DOI: 10.1351/pac200577010025.

16. Balendiran GK, Dabur R, Fraser D. The role of glutathione in cancer. Cell Biochem Funct . 2004 Nov-Dec; 22(6):343-52. Review. PMID:
      15386533 [PubMed - indexed for MEDLINE]

17. Dabur R, Ali M, Singh H, Gupta J, Sharma GL. A novel antifungal pyrrole derivative from Datura metel leaves. Pharmazie. 2004 Jul; 59(7)
      :568-70. PMID: 15296098 [PubMed - indexed for MEDLINE]

18. Dabur R, Singh H, Chhillar AK, Ali M, Sharma GL. Antifungal potential of Indian medicinal plants. Fitoterapia. 2003 Jun; 75(3-4):389-91.
      PMID: 15159003 [PubMed - indexed for MEDLINE]

19. A.K. Ashok, V. Kumar, P. Arya, S. Kumar, R. Dabur, N. Singh, A.K. Chhillar, G.L. Sharma, B. Ghosh, J. Wengel , C.E. Olsen and V.S.
      Parmar: Investigations towards new lead compounds from medicinally important plants. In Proceedings of bioresources towards
     drug discovery and development (2004)
, p. 213-235, ISBN No: 99903-73-16-7.

20. Clark J, Shevchuk T, Swiderski PM, Dabur R, Crocitto LE, Buryanov YI, Smith SS. Mobility-shift analysis with microfluidics chips.
      Biotechniques
. 2003 Sep; 35(3):548-54. PMID: 14513560 [PubMed - indexed for MEDLINE]

21. Rajesh and Sharma G L (2002). Studies on antimycotic properties of Datura metel . J Ethanopharmacol (80) 193-197. [PubMed -
       indexed for MEDLINE]

22. Dabur R, Mandal TK, Gurav AM, Singh DD. Bajpai V, GS Lavekar. (2007). Antibacterial and Antifungal Potential of some Indian medicinal
      plants Afr J Trad CAM. 4(3):319-322.

23. Dabur R, Mandal TK, Gurav AM, Tasleem Arif, Singh DD. Bajpai V, Chandra K. (2007). Antibacterial and Antifungal Potential of two
      Blumea species used in folkloric medicine. Bull Medico-Ethno- Bot. Res . (In Correspondence).

Books

1.Jarrod Clark; Taras Schevchuk; Piotr M Swiderski; Rajesh Dabur; Laura E Crocitto; Yaroslav I Buryanov and Steven S Smith (2003).
   Construction of Ordered protein Arrays
. Academic Press, Inc. A Division of Harcourt Brace & Company, 525 B Street, Suite1900, San
   Diego, California, 92101-4495.

2.K. Chandra, BG Choudhary, Rajesh Dabur, TK Mandal, AM Gurav, MB Yelne (2007). Database of Important Medicinal Plants
   Volume-VIII.
CCRAS Press, Govt of India, New Delhi. In Press.

 
Visits


December, 2001                     State University of New York (SUNY) at Stony Brook, New York.

March, 2001                            Beckman Research Centre, Duarte , California, USA.

June-August 2002                   Stanford University, Stanford, California, USA.

January  2003                          Harvard Institute of Medicine, Boston, MA, USA.























 



































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